Growth factors are naturally occurring proteins responsible for stimulating cell proliferation, inflammation modulation, angiogenesis and cellular bioactivity. They regulate the growth, maturation, function and repair of bone, muscle, connective tissue, nervous system and skin.

Growth factors can repair and regenerate aged and damaged skin, promoting collagen and elastin production to reduce lines and wrinkles, while improving the tone and texture of skin.

Exosomes are microscopic vesicles that transport essential cellular components, such as growth factors, nucleic acids, cytokines, and lipids, between cells. This process of intercellular communication allows exosomes to aid in the repair and renewal of aged or damaged cells, resulting in noticeable improvements in the health and appearance of skin and hair.

They help boost collagen production, support the development of new blood vessels (angiogenesis), reduce melanin production, enhance tissue regeneration, strengthen skin structure and cohesion, and provide anti-inflammatory effects for the skin.

The term "secretome" refers to a collection of molecules that are secreted, released, or shed into the extracellular space by a variety of cells. The secretome includes numerous bioactive molecules, with growth factors, cytokines, and exosomes being key components.

Benefits of secretomes derived from bovine colostrum for skin:

• The richest natural source of bioactive elements

• Free from genetic material

• Biocompatible with human skin

• Highly versatile

• Possess anti-inflammatory properties

• Among the most e?ective natural enhancers for skin rejuvenation treatments

Bovine colostrum is the early milk produced by cows shortly after giving birth. Packed with antibodies, growth factors, proteins, vitamins, and minerals, it has been utilized by humans for centuries due to its health benefits, such as enhancing immune function and supporting gastrointestinal health.

The biologically active compounds found in bovine colostrum include carbohydrates, proteins, fats, vitamins, minerals, antioxidants, cytokines, lactoferrin, lactoperoxidase, lysozyme, immunoglobulins (IGs), growth factors, and exosomes.

Bovine colostrum, containing over 250 biologically active compounds, o?ers numerous welldocumented health benefits. It is a particularly rich source of growth factors and is also high in antibodies, antioxidants, cytokines, lactoferrin, and lactoperoxidase, all of which play a vital role in promoting the regeneration of skin and hair.

Bovine colostrum contains lower levels of lactose and higher protein content, making it highly effective for these purposes.

The bovine colostrum used in AMPLEX Plus is ethically sourced from cattle raised on an Organic Certified, family-owned farm in Italy. The cows are grass-fed, and the colostrum is collected within one to five hours after birth to guarantee its premium quality.

Prior to harvesting, careful measures are taken to ensure that calves receive the necessary colostrum for their growth and development, preventing any deprivation.

The development of AMPLEX Plus involved nine years of collaboration between the Dermoaroma team and top European scientists to create a skin and hair care solution that is both safe and sustainable.

The product utilizes bovine colostrum, sourced from grass-fed cattle on an Organic Certified family farm in Italy, collected within one to five hours after birth. This method ensures that calves are never deprived of the colostrum necessary for their growth and development.

Once harvested, the colostrum is transported in specially equipped vehicles to the Dermoaroma production facility within 24 to 48 hours. Upon arrival, it undergoes a purification process to extract only the most potent biologically active components. Using centrifugation, exosomes and growth factors are isolated, while impurities such as fat, dead cells, and debris are removed.

The exosomes and growth factors are then subjected to a reliable dehydration method that allows them to be stored at room temperature without compromising their integrity and effectiveness. The final product consists of 5ml vials containing 200mg of 20 billion exosomes and 20 powerful growth factors, ready for use.

AMPLEX Plus has been proven to be entirely safe and non-toxic, thanks to its rapid harvesting method and thorough purification process.

It is free from artificial ingredients, poses no risk of infection transmission, and raises no ethical concerns regarding its use.

Being a lyophilized product, AMPLEX Plus is also easy to transport and store without compromising its quality.

Purasomes products are suitable for all skin types, although we advise against using them on individuals who are pregnant or breastfeeding.

Since the colostrum in AMPLEX Plus technology is derived from cattle, Purasomes may not be suitable for some vegan individuals.

AMPLEX Plus is both Halal and Kosher certified.

Purasomes are designed to deeply penetrate the skin through in-clinic microneedling, either as

a standalone treatment or in combination with other aesthetic procedures.

After completing a series of three to five treatment sessions, patients can expect noticeable

improvements in their skin and hair, with results lasting between 9 to 12 months. To maintain

these benefits, continued treatment every 6 months are recommended.

Purasomes serve as an excellent primer for energy-based treatments and can help accelerate skin recovery when used post-treatment. They can also be combined with polynucleotides to enhance overall results.